Dependence on zolpidem
نویسندگان
چکیده
منابع مشابه
Zolpidem dependence case series: possible neurobiological mechanisms and clinical management.
Zolpidem is a short-acting imidazopyridine hypnotic that is an agonist at the gamma-aminobutyric acid A type (GABAA) receptor. It has been suggested that it acts selectively on alpha1 subunit-containing GABAA benzodiazepine (BZ1) receptors presenting (contrary to classic benzodiazepines) low or no affinity for other subtypes. Therefore, it has been proposed that it lacks the benzodiazepines-lik...
متن کاملZolpidem dependence and withdrawal seizure--report of two cases.
Zolpidem is a non-benzodiazepine property which binds selectively to the ?1-GABAA receptors, and has been widely prescribed to patients suffering from insomnia. We report two cases of zolpidem dependence with withdrawal seizure in the Asian population. The first case is a 43-year-old woman who took zolpidem up to the dosage of 200 to 400 mg per night. The second case is a 35-year-old woman who ...
متن کاملZolpidem dependence, abuse and withdrawal: A case report
Zolpidem, a nonbenzodiazepine hypnotic, binds to the benzodiazepine binding site on the gamma-aminobutyric acid type A (GABA-A) receptors. Many studies have reported efficacy and safety of zolpidem in treatment of insomnia, low abuse, and dependence capability. However, many cases of zolpidem abuse and dependence were reported around the world. This case showed that zolpidem can exert abuse cap...
متن کاملA case of suicide attempt with Zolpidem - will Zolpidem show up on standard urine toxicology screening?
We describe a case of deep stupor after a suicide attempt with Zolpidem (Stillnox). A 64 year old patient was admitted unconscious to the emergency room. According to the medical document brought by his family, the patient was recently diagnosed with APLA syndrome, had 2 previous CVAs, the last one, having been located in the occipital lobe, resulted in cortical blindness. His wife described sh...
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ژورنال
عنوان ژورنال: Psychiatry and Clinical Neurosciences
سال: 2007
ISSN: 1323-1316,1440-1819
DOI: 10.1111/j.1440-1819.2007.01644.x